![]() Differential diagnoses for low ALP activity are mentioned in this case report. According to direct relationship between serums intact PTH and ALP in primary hyperparathyroidism, any failure in increasing levels of ALP, draw our attention to a range of diseases. It is the most important topic in this presentation. ![]() An interesting issue that drew our attention was the elevation of serum PTH level, despite the normal serum ALP concentration. Parathyroid disease also frequently leads to osteoporosis, kidney stones, hypertension, cardiac arrhythmias, and kidney failure. We present, an 89-year-old woman who initially manifested acute renal failure due to hypercalcemia and, finally, was diagnosed parathyroid adenoma. The most common symptoms of hyperparathyroidism are chronic fatigue, body aches, difficulty sleeping, bone pain, memory loss, poor concentration, depression, and headaches. Muscle aches or cramps in the legs, feet, stomach or face. This condition is known as tetany, which causes twitching and painful spasms in muscles of the face, hands, arms, throat and, sometimes, the feet. To prepare for parathyroidectomy surgery (removal of your parathyroid glands), we’ll order an imaging test to help locate the abnormal parathyroid gland or glands. ![]() The most common symptom is muscle cramps or tightness and tingling of the lips or fingers. If you have more severe symptoms and high blood calcium levels, we may talk to you about surgery to remove your parathyroid gland or glands. High serum PTH levels are associated with elevated alkaline phosphatase (ALP) levels in the general population. Signs and symptoms can include: Tingling or burning in the fingertips, toes and lips. The symptoms of hypoparathyroidism result from the low levels of calcium in the body. Long-standing elevated serum calcium level can lead to renal insufficiency. Primary hyperparathyroidism is relatively an uncommon condition, where the majority of cases present asymptomatically after biochemical testing showing a mild hypercalcemia and elevated parathyroid hormone (PTH) level.
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